Summary Table of "C" Recommendations
When Evidence is Conflicting

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Please note: In 2003, the CTF updated its Grades of Recommendations to include an "I Recommendation" for situations where insufficient evidence exists to allow a recommendation to be made.  (Formerly, these situations were captured under a "C Recommendation".)  This change is not retroactive, and all "C Recommendations" made prior to 2003 have not been reevaluated in light of the new "I" recommendation grade.  For a discussion of these recommendation grades, please link to the 2003 article in the Canadian Medical Association Journal here.

 
CONDITION MANEUVER POPULATION
Abdominal aortic aneurysm Abdominal palpation General population
Abdominal aortic aneurysm Abdominal ultrasound General population
Adverse consequences, children of alcoholics Routine evaluation; some screening options General population
Adverse consequences, children of alcoholics Referral school- or community-based intervention programs High-risk population
Age-related macular degeneration Fundoscopy Elderly
All-cause mortality and morbidity Counselling, physical activity; prevent obesity General population
All-cause mortality, morbidity Measure body mass index and treat obesity General population
All-cause morbidity and mortality Office contact or home-based parenting education programs Disadvantaged children
Breast cancer Screening mammography Women aged 40-49 years at average risk of breast cancer
Breast cancer follow-up Follow-up for local recurrence Women having been previously diagnosed with breast cancer
Breast cancer follow-up Follow-up for contralateral breast cancer Women having been previously diagnosed with breast cancer
Bladder cancer Urine dipstick or cytology High-risk males >60 years 
Cardiovascular disease Acetylsalicylic acid prophylaxis General population
Carotid disease/ stroke Antiplatelet therapy  Adults with asymptomatic carotid bruit or stenosis
Child maltreatment Comprehensive health care program Families with children
Child maltreatment Parent education and support program Families with children
Child maltreatment Combination of home-based services,
including case management, 
education and psychotherapy
Families with children
Child maltreatment Sexual abuse, abduction prevention programs General population
Cognitive impairment Mental status screening Elderly
Colorectal cancer Hemoccult/sigmoidoscopy in combination Average risk adults > age 50
Colorectal cancer Colonoscopy Average risk adults, high-risk adults with family history of polyps/CRC
Congenital rubella syndrome Universal vaccination Young men (living in crowded conditions) 
Coronary artery disease events Screening for total plasma homocysteine levels General population or those at high risk for coronary artery disease events
Coronary artery disease events Vitamin therapy (folic acid alone or with vitamin B12) to lower total plasma homocysteine levels All populations
Coronary heart disease Diet/drug treatment Individuals with elevated cholesterol or LDL-C except males 30-59 yrs
Coronary heart disease Measurement of blood total cholesterol level General population with case-finding for males 30-59 years 
Coronary heart disease General dietary advice on fat and cholesterol General population except males 30-69 years 
D (Rh) sensitization Repeat D (Rh) antibody screening and immunoglobin (D Ig) administration Women undergoing specific obstetric procedures or complications
Dental caries Counselling, diet or baby bottle General and high-risk population 
Developmental Hip Dysplasia Abduction therapy Normal- or high-risk infant
Developmental Hip Dysplasia Timing of abduction therapy (early intervention) - optimal duration of observation Normal- or high-risk infants
Developmental problems Developmental screening questionnaires Preschool children
Domestic violence Batterer/couples interventions General population
Elder abuse Elder abuse questionnaire Elderly
Fetal alcohol syndrome History, questionnaire, interview, clinical judgment/alcohol consumption Pregnant women
Gestational diabetes mellitus Blood glucose, fasting/random or glucose challenge test Pregnant women
Gestational diabetes mellitus History, risk factors; if positive glucose tolerance test Pregnant women
Glaucoma Fundoscopy, tonometry or automated perimetry Elderly
Group B Streptococcal Intrapartum chemoprophylaxis based on risk factors only Pregnant women
Hemoglobinopathies Screening for carrier status and counselling Adult population and non-pregnant adolescents
HIV/AIDS History, sexual and drug use counselling General population
HIV/AIDS Voluntary HIV antibody screening General population including pregnant women
Household and recreational injury Counselling, household and recreational injury (except some home hazards, poisoning for children) Children, adults, elderly
Household and recreational injury Public education/ Legislation, gun control & use of Heimlich maneuver General population
Household and recreational injury Monitor medical impairment Elderly
Household and recreational injury Public education, non-flammable fabrics, self-extinguishing cigarettes Elderly
Hypertension Pharmacologic treatment  Adults aged <21 yrs, isolated systolic hypertension, some elderly subgroups
Idiopathic adolescent scoliosis Physical exam, back Adolescents 
Influenza Immunization, annual General population <65 years 
Influenza Rapid diagnostic test Suspected cases
Iron deficiency anemia Routine hemoglobin General population and infants
Lead exposure Universal screening (Blood lead level or questionnaire) General population
Low birth weight Iron supplementation Pregnant women
Low birth weight/preterm birth Diet supplementation Pregnant women at high risk of undernutrition
Low birth weight/preterm birth Multicomponent programs Pregnant women
MVA injury Counselling, helmet, alcohol use General population
MVA injury Monitor medical impairment General population
Neonatal herpes simplex Cesarean section Symptomatic pregnant women 
Neonatal morbidity and mortality Electronic fetal monitoring, intrapartum  High-risk pregnancies
Obesity BMI measurement General population
Obesity Community-based obesity prevention programs General population
Obesity Weight-reduction therapy Obese adults without obesity-related disease
Obesity Exercise and/or nutrition and behaviour modification Obese children
Obesity Height, weight, skin-fold thickness, BMI, etc. Children 
Occupational low back pain Use of back belts in the workplace General population
Oral cancer - 1994 review Physical exam, oral cavity  General population
Oral cancer - 1999 review Screening by clinical examination Asymptomatic patients
Otitis Media Screening to identify children with clinically important
OME (tympanometry,
microtympanometry, acoustic
reflectometry and pneumo-otoscopy)
Children up to 4 years of age
Otitis Media Screening to prevent delay in language development as a
result of OME
Children up to 4 years of age
Ovarian cancer Pelvic exam, transvaginal ultrasound, CA 125 or combination Pre- and post-menopausal women or family history 1st degree relative
Paroxysmal atrial fibrillation
in patients with stroke
Ambulatory ECG All patients presenting with stroke or transient ischemic attack
Perinatal morbidity and mortality Ultrasound, prenatal, serial Pregnant women
Periodontal disease Brushing and flossing teeth, supervised High-risk patients
Periodontal disease Brushing with electric toothbrush  Patients with limited dexterity
Periodontal disease Flossing teeth  Children
Phenylketonuria Phenylalanine test Pregnant women
Pneumococcal pneumonia Immunization, one dose Immunocompetent elderly living independently 
Preeclampsia Aspirin prophylaxis, low dose Pregnant women
Preterm birth Home uterine activity monitoring High-risk pregnancies 
Prostate cancer Digital rectal examination Males >50 years 
Protein/calorie malnutrition Protein/calorie malnutrition screening  Adult population
Skin cancer Counselling, Skin self-examination General population
Skin cancer Counselling, Sun block General population
Skin cancer Physical examination, skin General population
Stroke Ambulatory ECG All patients presenting with stroke or transient ischemic attack
Stroke Echocardiography: Transthoracic (TTE) or transesophageal (TEE) for detection of intracardiac masses Patients without clinical cardiac disease
Stroke Treatment for patent foramen ovale General population
Suicide Suicide risk evaluation General population
Suicide Referral school- or community-based program High-risk population
Suicide Hospital admission, discharge home, intensive psycho-social follow-up Individuals previously attempting suicide
Testicular cancer Physical exam or self-examination Adolescent or adult males
Thyroid cancer Neck Palpation Adult population
Thyroid disorders Thyroid stimulating hormone test  Perimenopausal women 
Tobacco-caused disease Counselling on environmental tobacco smoke Families with smokers
Tuberculosis INH Prophylaxis General population aged >35 years 
Urinary infection Urine dipstick or culture Elderly, ambulatory women 

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