Asymptomatic Carotid Disease

Prepared by Ariane Mackey, MD, FRCPC, Fellow (Cerebro-Vascular), Division of Neurology, Department of Medicine, Robert Cote, MD, FRCPC, Division of Clinical Epidemiology, and Renaldo N. Battista, MD, ScD, FRCPC, Director, Division of Clinical Epidemiology, Montreal General Hospital

1. Heart and Stroke Foundation of Canada: Cardiovascular Disease in Canada. 1993

2. Mayo NE: Epidemiology and recovery. In: Physical medicine and rehabilitation: state of the art reviews. Philadelphia: Hanley & Belfus, 1993; 7: 1-25

3. Zhu CZ, Norris JW: Role of carotid stenosis in ischemic stroke. Stroke 1990; 21: 1131-1134

4. Heyman A, Wilkinson WE, Heyden S, et al: Risk of stroke in asymptomatic persons with cervical arterial bruits: a population study in Evans County, Georgia. N Engl J Med 1980; 302: 838-841

5. Wolf PA, Kannel WB, Sorlie P, et al: Asymptomatic carotid bruit and risk of stroke. The Framingham Study. JAMA 1981; 245: 1442-1445

6. Roederer GO, Langlois YE, Jager KA, et al: The natural history of carotid arterial disease in asymptomatic patients with cervical bruits. Stroke 1984; 15: 605-613

7. Norris JW, Zhu CZ, Bornstein NM, et al: Vascular risks of asymptomatic carotid stenosis. Stroke 1991; 22: 1485-1490

8. Meissner I, Wiebers DO, Whisnant JP, et al: The natural history of asymptomatic carotid artery occlusive lesions. JAMA 1987; 258: 2704-2707

9. Autret A, Pourcelot L, Saudeau D, et al: Stroke risk in patients with carotid stenosis. Lancet 1987; 1: 888-890

10. Mackey A, Côté R, Abrahamowicz M, et al: Outcome of patients with asymptomatic bruits. Neurology 1993; 43: A351 [abstract]

11. Wiebers DO, Whisnant JP, Sandok BA, et al: Prospective comparison of a cohort with asymptomatic carotid bruit and a population-based cohort without carotid bruit. Stroke 1990; 21: 984-988

12. AbuRahma AF, Robinson PA: Prospective clinicopathophysiologic follow-up study of asymptomatic neck bruit. Am Surg 1990; 56: 108-113

13. Hennerici M, Hulsbomer HB, Hefter H, et al: Natural history of asymptomatic extracranial arterial disease. Results of a long term prospective study. Brain 1987; 110: 777-791

14. Lusiani L, Visona A, Castellani V, et al: Prevalence of atherosclerotic lesions of the carotid bifurcation in patients with asymptomatic bruits: an echo-Doppler (duplex) study. Angiology 1985; 36: 235-239

15. Chambers BR, Norris JW: Clinical significance of asymptomatic neck bruits. Neurology 1985; 35: 742-745

16. Floriani M, Giulini SM, Bonardelli S, et al: Value and limits of "critical auscultation" of neck bruits. Angiology 1988; 39: 967-972

17. Ingall TJ, Homer D, Whisnant JP, et al: Predictive value of carotid bruit for carotid atherosclerosis. Arch Neurol 1989; 46: 418-422

18. Goldman L, Koller RL, Lebow SS, et al: Cervical bruits: clinical correlated of stenosis. Angiology 1991; 42: 491-497

19. Kuller LH, Sutton KC: Carotid artery bruit: Is it safe to and effective to auscultate the neck? Stroke 1984; 15: 944-947

20. Caplan LR: Carotid artery disease. N Engl J Med 1986; 315: 886-888

21. Feussner JR, Matchar DB: When and how to study the carotid arteries. Ann Int Med 1988; 109: 805-818

22. Bornstein NM, Chadwick LG, Norris JW: The value of carotid Doppler ultrasound in asymptomatic extracranial arterial disease. Can J Neurol Sci 1988; 15: 378-393

23. Qizilbash N, Duffy SW, Warlow C, et al: Lipids are risk factors for ischaemic stroke: overview and review. Cerebrovas Dis 1992; 2: 127-136

24. The Asymptomatic Cervical Bruit Study Group: Natural history and effectiveness of aspirin in asymptomatic patients with cervical bruits. Arch Neurol 1991; 48: 683-686

25. Antiplatelet Trialists' Collaboration: Collaborative overview of randomized trials of antiplatelet treatment. Part 1: prevention of death, myocardial infarction and stroke by prolonged antiplatelet therapy in various cateories of patients. Br Med J 1994; 308: 81-106

26. Mayo Asymptomatic Carotid Endarterectomy Study Group: Results of a randomized controlled trial of carotid endarterectomy for asymptomatic carotid stenosis. Mayo Clin Proc 1992; 67: 513-518

27. The CASANOVA Study Group: Carotid surgery versus medical therapy in asymptomatic carotid stenosis. Stroke 1991; 22: 1229-1235

28. Hobson RW, Weiss DG, Fields WS, et al: Efficacy of carotid endarterectomy for asymptomatic carotid stenosis. N Engl J Med 1993; 328: 221-227

29. North American Symptomatic Carotid Endarterectomy Trial Collaborations: Beneficial effect of carotid endarterectomy in symptomatic patients with high grade carotid stenosis. N Engl J Med 1991; 325: 445-453

30. European Carotid Surgery Trialist Collaboration Group: MRC European Carotid Surgery Trial: interim results for symptomatic patients with severe (70-99%) or mild (0-29%) carotid stenosis. Lancet 1991; 337: 1235-1243

31. The Asymptomatic Carotid Atherosclerosis Study Group: Study design for randomized prospective trial of carotid endarterectomy for asymptomatic atherosclerosis. Stroke 1989; 20: 844-849

32. Gerraty RP, Gates PC, Doyle JC: Carotid stenosis and perioperative stroke risk in symptomatic and asymptomatic patients undergoing vascular or coronary surgery. Stroke 1993; 24: 1115-1118

33. Brener BJ, Brief DK, Alpert J, et al: The risk of stroke in patients with asymptomatic carotid stenosis undergoing cardiac surgery: a follow-up study. J Vasc Surg 1987; 5: 269-279

34. Bass A, Krupski WC, Dilley RB, et al: Combined carotid endarterectomy and coronary artery revascularisation: a sobering review. Isr J Med Sci 1992; 28: 27-32