Canadian Task Force on Preventive Health Care

Selected References

Preventive Health Care, 2000 Update:  Screening for Otitis Media with Effusion

Prepared  by Christopher C. Butler, BA, MBChB, DCH, MRCGP, CCH, MD, and Harriet MacMillan, MD, MSc, FRCP(C) with the Canadian Task Force on Preventive Health Care

These recommendations were finalized by the Task Force in September 2000.

  1. Feightner JW.  Canadian Task Force on the Periodic Health Examination, editors. The Canadian guide to clinical preventive health care. Ottawa: Health Canada;  1999; 27, Routine pre-school screening for visual and hearing problems. p. 298-303.

  2. Stool SE; Berg AO; Berman S, et al.  Otitis media with effusion in young children.  Clinical practice guideline. Number 12. Rockville, MD: Agency for Health Care Policy and Research, Public Health Services, US Department of Health and Human Services; 1994.

  3. Lous J. Secretary otitis media in schoolchildren: Is screening for secretary otitis media advisable?  Danish Med Bull  1995;71-99.

  4. Freemantle N, Sheldon TA, Song F, and Long A. The treatment of persistent glue ear in children:  Are surgical interventions effective in combating disability from glue ear? Effective Health Care  1992;4.

  5. Vernon-Feagans L, Emanuel DC, Blood I. The effect of otitis media and quality of day care on children's language development.  J Appl Dev Psychol  1997;18(395):395-409

  6. Feagans LV, Kipp E, Blood I. The effect of otitis media on the attention skills of day-care-attending toddlers.  Devel Psychol  1994;30:701-8.

  7. Elden LM, Coyte PC. Socioeconomic impact of otitis media in North America.  J Otolaryngol  1998;27(Suppl 2):s9-s16

  8. Gates GA. Cost effectiveness considerations in otitis media treatment.  Otolaryngol Head Neck Surg  1996;114:525-30.

  9. Culpepper L, Froom J. Otitis media with effusion in young children: Treatment in search of a problem?  J Am Board Fam Pract  1995;8:305-16.

  10. Woolf S, Battista RN, Geoffrey M. Assessing the clinical effectiveness of preventive maneuvers: analytic principles and systematic methods in reviewing evidence and developing clinical practice recommendations.  J Clin Epidemiol  1990;43(9):891-905.

  11. Canadian Task Force on the Periodic Health Examination. The periodic health examination.  Can Med Assoc J  1979;121:1193-254.

  12. Battista R, Fletcher S.  Battista R, Lawrence R, editors.Implementing preventive services. New York: Oxford University Press;  1988;Making recommendations on preventive practices: methodological issues. p. 53-67.

  13. Bishop D, Edmundson A. Is otitis media a major concern of specific developmental language disorders?  Br J Disord Commun  1986;21:321-38.

  14. Brookhouser PE, Goldgar DE. Medical profile of the language-delayed child: otitis prone versus otitis free.  In J of Ped Otorhinolaryngol  1987;12:237-71.

  15. Holm VA, Kunze LVH. Effect of chronic otitis media on language and speech development.  Pediatrics  1969;43:833-9.

  16. Jerger S, Jerger J, Alford BR, Abrams S. Development of speech intelligibility in children with recurrent otitis media.  Ear Hear  1983;4:138-45.

  17. Needleman H.  Jaffe BF, editors.Hearing loss in children.  A comprehensive text. Baltimore: University Park Press;  1977;Effects of hearing loss from early recurrent otitis media on speech and language development. p. 640-9.

  18. Paradise JL. Management of middle ear effusions in infants with cleft palate.  Ann Otol Rhinol Laryngol  1976;85(Suppl 25):s285-s288.

  19. Sak RJ, Ruben RJ. Recurrent middle ear effusion in childhood: implications of temporary auditory deprivation for language and learning.  Ann Otol  1981;90:546-51.

  20. Bennett KE, Haggard MP. Behaviour and cognitive outcomes from middle ear disease.  Arch Dis Child  1999;80:28-35.

  21. Webster A, Bamford JM, Thyer NJ, Ayles R. The psychological, educational and auditory sequelae of early, persistent secretary otitis media.  J Clin Psychol Psychiat  1989;30:529-46.

  22. Haggard MP, Birkin JA, Browning GG, Gatehouse S, Lewis S. Behaviour problems in otitis media.  Pediatr Infect Dis  1994;13:s43-s50.

  23. Bax M, Hart H, Jenkins S. The behaviour, development, and health of the young child: implications for care.  BMJ  1983;286:1793-6.

  24. Bax M.  Brown CC, editors.Infants at risk: pediatric roundtable 5.  1 ed. New Brunswick NJ: Johnson and Johnson;  1981;The intimate relationship of health, development and behaviour in the young child. p. 106-13.

  25. Luotonen M, Uhari M, Aitola L, Lukkaroinen A-M, Luotonen J, Korkeamaki R-L. Recurrent otitis media during infancy and linguistic skills at age of nine years.  Pediatr Infect Dis J  1996;15:854-8.

  26. Lehmann MD, Charron K, Kummer A, Keith RW. The effects of chronic middle ear effusions on speech and language development; a descriptive study.  Int J Pediatr Otorhinol  1979;1:137-44.

  27. Zinkus PW, Gottlieb MI, Schapiro M. Developmental and psychoeducational sequelae of chronic otitis media.  Am J Dis  1978;132:1100-4.

  28. Zinkus PW, Gottlieb MI. Patterns of perceptual and academic deficits related to early chronic otitis media.  Ped  1980;66:246-53.

  29. Winitz H, Darley FL.  Lassman FM, Fisch RO, Vetter DK, LaBenz ES, editors.Early correlates of speech, language and hearing. Littlejohn: PSG Publishing Company;  1980;Speech production. p. 232-65.

  30. Brandes PJ, Ehinger DM. The effect of early middle ear pathology on auditory perception and academic achievement.  J Speech Hear Disord  1981;46:250-7.

  31. Shriberg LD, Flipsen P, Thielke HM, Kwiatkowski J, Kertoy MK, Katcher ML, Nellis RA, Block MG. Risk for speech disorder associated with early recurrent otitis media with effusion: two retrospective studies.  J Speech Lang Hear Res  2000;43:79-99.

  32. Black MM, Gerson LF, Freeland CAB, Nair P, Rubin JS, Hutcheson JJ. Language screening for infants prone to otitis media.  J Pediatr Psychol  1988;13:423-33.

  33. Hartsen G, Nettelbladt U, Schalen L, Kalm O, Prellner K. Language development in children with recurrent acute otitis media during the first three years of life: follow up study from birth to seven years of age.  J Laryngol Otol  1993;107:407-12.

  34. Paul R, Lynn TF, Lohr-Flanders M. History of middle ear involvement and speech/language development in late talkers.  J Speech Hear Res  1993;36:1055-62.

  35. Rvachew S, Slawinski EB, Williams M, Green CL. The impact of early onset otitis media on babbling and early language development.  Acoust Soc Am  1999;105:467-75.

  36. Allen DV, Robinson DO. Middle ear status and language development in preschool children.  ASHA  1984;26:33-7.

  37. Van Cauwenberge P, Van Cauwenberge K, Kluyskens P. The influence of otitis media with effusion on speech and language development and psycho-intellectual behaviour of the preschool child-results of a cross sectional study in 1512 children.  Auris Nasus Larynx  1985;12(suppl 1):s228-s230.

  38. Friel-Patti S, Finitzo-Hierber T, Conti G, Brown KC. Language delay in infants associated with middle ear disease and mild, fluctuating hearing impairment.  Pediatr Infect Dis  1982;1:104-9.

  39. Pearce PS, Saunders MA, Creighton DE, Sauve RS. Hearing and verbal-cognitive abilities in high risk pre-term infants prone to otitis media with effusion.  J Dev Behav Pediatr  1988;9:346-52.

  40. Wallace IF, McCarton CM, Bernstein RS, Gravel JS, Stapells DR, Ruben RJ. Otitis media, auditory sensitivity, and language outcomes at one year.  Laryngoscope  1988;98:64-70.

  41. Wallace IF, Gravel JS, McCarton CM, Ruben RJ. Otitis media and language development at one year of age.  J Speech Hearing Dis  1988;53:245-51.

  42. Abraham SS, Wallace IF, Gravel JS. Early otitis media and phonological development at age 2 years.  Laryngoscope  1996;106:727-32.

  43. Wallace IF, Gravel JS, Schwartz RG, Ruben RJ. Otitis media, communication style of primary caregivers, and language skills of 2 year olds: a preliminary report.  J Dev Behav Pediatr  1996;17:27-35.

  44. Gravel JS, Wallace IF. Listening and language at 4 years of age: effects of early otitis media.  J Speech Hear Res  1992;35:588-95.

  45. Gravel JS, Wallace IF. Early otitis media, auditory abilities, and educational risk.  Am J Speech Lang Path  1995;4:89-94.

  46. Hubbard TW, Paradise JL, McWilliams BJ, Elster BA, Taylor FH. Consequences of unremitting middle-ear disease in early life.  Otologic, audiologic and developmental findings in children with cleft palate.  N Engl J Med  1985;312:1529-34.

  47. Schonweiler R, Schonweiler B, Schmelzeisen R. Hearing capacity and speech production in 417 children with facial cleft abnormalities.  HNO  1994;42:691-6.

  48. Roberts JE, Burchinal MR, Koch MA, Footo MM, Henderson FW. Otitis media in early childhood and its relationship to later phonological development.  J Speech Hearing Dis  1988;53:424-32.

  49. Roberts JE, Burchinal MR, Collier AM, Ramey CT, Koch MA, Henderson FW. Otitis media in early childhood and cognitive, academic, and classroom performance of the school-aged child.  Pediatrics  1989;83:477-85.

  50. Roberts JE, Burchinal MR, Medley LP, Zeisel SA, Munday M, Roush J, Hooper SR, Bryant D, Henderson FW. Otitis media, hearing sensitivity, and maternal responsiveness in relation to language during infancy.  J Pediatr  1995;126:481-9.

  51. Roberts JE, Burchinal MR, Zeisel SA, Neede EC, Hooper SR, Roush J, Bryant D, Mundy M, Henderson FW. Otitis media, the caregiver environment, and language and cognitive outcomes at 2 years.  Pediatrics  1998;102:346-54.

  52. Roberts JE, Burchinal MR, Davis BJ, Collier AM, Henderson FW. Otitis media in early childhood and later language.  J Speech Hearing Res  1991;34:1158-68.

  53. Arcia E, Roberts JE. Otitis media in early childhood and its association with sustained attention in structured situations.  J Dev Behav Pediatr  1993;14:181-3.

  54. Roberts JE, Sanyal MA, Burchinal MR, Collier AM, Ramey CT, Henderson FW. Otitis media in early childhood and its relationship to later verbal and academic performance.  Pediatrics  1986;78:423-30.

  55. Roberts JE, Burchinal MR, Clarke-Klein SM. Otitis media in early childhood and cognitive, academic, and behavior outcomes at 12 years of age.  J Pediatr Psychol  1995;20:645-60.

  56. Lewis N. Otitis media and linguistic incompetence.  Arch Otolaryngol  1976;102:387-90.

  57. Fishler RS, Todd NW, Feldman CM. Otitis media and language performance in a cohort of Apache Indian children.  AJDC  1985;139:355-60.

  58. Kaplan GJ, Fleshman JK, Bender TR, Baum C, Clark PS. Long-term effects of otitis media.  A ten-year cohort study of Alaskan Eskimo children.  Pediatrics  1973;52:577-85.

  59. Saim A, Saim L, Saim S, Ruszymah BH, Sani A. Prevalence of otitis media with effusion amongst pre-school children in Malaysia.  Int J Pediatr Otorhinol  1997;41:21-8.

  60. Nienhuys TG, Boswell JB, McConnel FB. Middle ear measures as predictors of hearing loss in Australian aboriginal schoolchildren.  In J of Ped Otorhinolaryngol  1994;30:15-27.

  61. Ogisi FO. Impedance screening for otitis media with effusion in Nigerian children.  J Laryngol Otol  1988;102:986-8.

  62. Thielke HM, Shriberg LD. Effects of recurrent otitis media on language, speech, and educational achievement in Menominee Indian children.  L Am Indian Educ  1990;29:25-35.

  63. Feagans L, Sanyal MA, Henderson FW, Collier AM, Appelbaum M. Relationship of middle ear disease in early childhood to later narrative and attention skills.  J Pediatr Psychol  1987;12:581-94.

  64. Silva PA, Chalmers D, Stewart I. Some audiological, psychological, educational and behavioural characteristics of children with bilateral otitis media with effusion: A longitudinal study.  J Learning Disabilities  1986;19:165-9.

  65. Brooks DN. Otitis media with effusion and academic attainment.  In J of Ped Otorhinolaryngol  1986;12:39-47.

  66. Brooks DN. Otitis media with effusion: academic attainment and socioeconomic background.  In J of Ped Otorhinolaryngol  1987;13:165-70.

  67. Lyn C, Jadusing WA, Ashman H, Chen D, Abramson A, Soutar I. Hearing screening in Jamaica: prevalence of otitis media with effusion.  Laryngoscope  1998;108:288-90.

  68. Barratt A, Irwig L, Galsziou P, Cummings RG, Raffle A, Hicks N, Muir Gray JA, Guyatt GH. Users' guides to the medical literature XVII.  How to use guidelines and recommendations about screening.  JAMA  1999;281:2029-34.

  69. Zielhuis GA, Rach GH, van den Broek P. Screening for otitis media with effusion in preschool children.  Lancet  1989;8633:311-3.

  70. Rach GH, Zielhuis GA, van Baarle PW, van den Broek P. The effect of treatment with ventilating tubes on language development in preschool children with otitis media with effusion.  Clin Otolaryngol  1991;16:128-32.

  71. Schilder AG, Van Manen JG, Zielhuis GA, Grievink EH, Peters SAF, van den Broek P. Long term effects of otitis media with effusion on language, reading and spelling.  Clin Otolaryngol  1993;18:234-41.

  72. Peters SAF, Grievink EH, van Bon WHJ, Schilder GM. The effects of early bilateral otitis media with effusion on educational attainment: a prospective cohort study.  J Learning Disabilities  1994;27:111-21.

  73. Peters SAF, Grievink EH, van Bon WHJ, van den Bereken JHL, Schilder AGM. The contribution of risk factors to the effect of early otitis media with effusion on later language, reading, and spelling.  Dev Med Child Neurol  1997;39:31-9.

  74. Grievink EH, Peters SAF, van Bon WHJ, Schilder AGM. The effect of early bilateral otitis media with effusion on language ability: A prospective cohort study.  J Speech Hearing Res  1993;36:1004-12.

  75. Rach GH, Zielhuis GA, van den Broek P. The influence of chronic persistent otitis media with effusion on language development of 2- to 4-year-olds.  In J of Ped Otorhinolaryngol  1988;15:253-61.

  76. Schilder AGM, Hak E, Straatman H, Zielhuis GA, van Bon WHJ, van den Broek P. Long-term effects of ventilation tubes for persistent otitis media with effusion in children.  Clin Otolaryngol  1997;22:423-9.

  77. Feldman W, Milner RA, Sackett B, Iberst S. Effects of preschool screening for vision and hearing on prevalence of vision and hearing problems 6-12 months later.  Lancet  1980;2:1014-6.

  78. Augustsson I, Nilson C, Engstrand I. The preventive value of audiometric screening of preschool and young school-children.  In J of Ped Otorhinolaryngol  1990;20:51-62.

  79. O'Mara LM, Isaacs S, Chambers LW. Follow-up of participants in a preschool hearing screening program in child care centres.  Can J Pub Health  1992;83:375-8.

  80. Crampton P, Bandaranayake D. Evaluation of an otitis media with effusion screening pilot program.  NZ Med J  1996;109:384-6.

  81. Lucker J. Application of pass fail criteria to middle ear screening results.  ASHA  1990;22:839-40.

  82. Roush J, Tait CA. Pure-tone and acoustic immittance screening of pre-school aged children: an examination of referral criteria.  Ear Hear  1985;6:245-50.

  83. Kimball S. Acoustic reflectometry: spectral gradient analysis for the improved detection of middle ear effusion in children.  Pediatr Infect Dis J  1998;17:552-5.

  84. Davis AC, Wood S. The epidemiology of childhood hearing impairment: factors relevant to planning of services.  Br J Audiol  1992;26:77-90.

  85. Cooper JC, Hearne EM, Gates GA. Normal tympanometric shape.  Ear and Hearing  1982;3:241-5.

  86. Finitzo T, Friel-Patti S, Chinn K, Brown O. Tympanometry and otoscopy prior to myringotomy: issues in diagnosis of otitis media.  In J of Ped Otorhinolaryngol  1992;24:101-10.

  87. Barnett ED, Klein JO, Hawkins KA, Cabral HJ, Kenna M, Healy G. Comparison of spectral gradient acoustic reflectometry and other diagnostic techniques for detection of middle ear effusion in children with middle ear disease.  Pediatr Infect Dis J  1998;17:556-9.

  88. Mills RP. Persistent middle ear effusions in children with recurrent acute otitis media.  Clin Otolaryngol  1987;12:97-101.

  89. Fiellau-Nikolajsen M. Tympanometry and middle ear effusion: a cohort study in three year old children.  In J of Ped Otorhinolaryngol  1980;2:39-49.

  90. Nozza RJ, Bluestone CD, Kardatzke D, Bachman R. Towards the validation of aural acoustic immittance measures for diagnosis of middle ear effusion in children.  Ear Hear  1992;13:442-53.

  91. Roush J, Drake A, Sexton JE. Identification of middle ear dysfunction in young children: A comparison of tympanometric screening procedures.  Ear Hear  1992;13:63-9.

  92. Page AR, Kramer S, Novak J, Williams D, Slymen D. Tympanometric screening in elementary school children.  Audiology  1995;34:6-12.

  93. Fields MJ, Allison RS, Corwin P, White PS, Doherty J. Microtympanometry, microscopy and tympanometry in evaluating middle ear effusions prior to myringotomy.  NZ Med J  1993;106:386-7.

  94. Vaughn-Jones R, Mills RP. The Welch Allyn audioscope and microtymp: their accuracy and that of pneumatic otoscopy, tympanometry and pure tone audiometry as predictors of otitis media with effusion.  J Laryngol Otol  1992;106:600-2.

  95. van Balen FAM. Validation of a portable tympanometer for use in primary care.  In J of Ped Otorhinolaryngol  1994;29:219-25.

  96. Koivunen P, Alho O-P, Uhari M, Niemela M, Luotonen J. Minitympanometry in detecting middle ear fluid.  J Pediatr  1997;131:419-42.

  97. De Melker RA. Diagostic value of microtympanometry in primary care.  BMJ  1992;304:96-8.

  98. Wazen JJ, Ferraro JA, Hughes R. Clinical evaluation of a portable, cordless, hand-held middle ear analyzer.  Otolaryngol Head Neck Surg  1988;99:348-50.

  99. Anonymous. Sensitivity, specificity and predictive value of tympanometry in predicting a hearing impairment in otitis media with effusion.  MRC Multi-Centre Otitis Media Study Group.  Clin Otolaryngol  1999;24:284-300.

  100. Dempster JH, Mackenzie K. Tympanometry in the detection of hearing impairments associated with otitis media with effusion.  Clin Otolaryngol  1991;16:157-9.

  101. Kzanas SG, Maw R. Tympanometry, stapedius reflex and hearing impairment in children with otitis media with effusion.  Acta Otolaryngol (Stockh)  1994;114:410-4.

  102. Schwartz DM, Schwartz RH. Validity of acoustic reflectometry in detecting middle ear effusion.  Pediatrics  1987;79:739-42.

  103. Babonis TR, Weir MR, Kelly PC. Impedance tympanometry and acoustic reflectometry at myringotomy.  Pediatrics  1991;87:475-80.

  104. Oyiborohoro JMA, Olaniyan SO, Newman CW, Balakrishnan SL. Efficacy of acoustic otoscope in detecting middle ear effusion in children.  Laryngoscope  1987;97:495-8.

  105. Douniadakis DE, Nikolopoulos TP, Tsakanikos MD, Vassiliadis SV, Apostolopoulos NJ. Evaluation of acoustic reflectometry in detecting otitis media in children.  Br J Audiol  1993;27:409-14.

  106. Combs JT. Predictive value of the angle of acoustic reflectometry.  Pediatr Infect Dis  1991;10:214-6.

  107. Block SL, Mandel E, Mclinn S, Pichichero ME, Bernstein S, Kimball S, Kozikowwski J. Spectral gradient acoustic reflectometry for the detection of middle ear effusion by pediatricians and parents.  Pediatr Infect Dis J  1998;17:560-4.

  108. Pellett FS, Cox LC, MacDonald CB. Use of acoustic reflectometry in the detection of middle ear effusion.  J Am Acad Audiol  1997;8:181-7.

  109. Silman S, Silverman CA, Arick DS. Acoustic-immittance screening for detection of middle-ear effusions in children.  J Am Acad Audiol  1992;3:262-8.

  110. Kemaloglu YK, Sever T, Beder L, Bayazit Y, Goksu N. Predictive value of acoustic reflectometry (angle and reflectivity) and tympanometry.  Int J Pediatr Otorhinol  1999;48:137-42.

  111. Buhrer K, Wall LG, Schuster L. The acoustic reflectometer as a screening device: A comparison.  Ear Hear  1985;6:307-14.

  112. Macknin ML, Skibinski C, Beck G, Hughes G, Kinney S. Acoustic reflectometry detection of middle ear effusion.  Pediatr Infect Dis J  1987;6:866-8.

  113. Avery CA, Gates GA, Prihoda TJ. Efficacy of acoustic reflectometry in detecting middle ear effusion.  Ann Otol Rhinol Laryngol  1986;95:472-6.

  114. Preston K. Pneumatic otoscopy: a review of the literature.  Issues in Comprehensive Pediatric Nursing  1998;21:117-1128.

  115. Takahashi H, Honjo I, Hasebe S, Sudo M, Tanabe M. The diagnostic and prognostic value of eardrum mobility in OME.  Eur Arch Oto Rhino Lanyngol  1999;256:189-91.

  116. Reves R, Budgett R, Miller D, Wadsworth J, Haines A. Study of middle ear disease using tympanometry in general practice.  BMJ  1985;290:1953-6.

  117. Bluestone CD, Cantekin EI. Design factors in the characterization and identification of otitis media and certain related conditions.  Ann Otol Rhinol Laryngol  1979;5 part 1:13-8.

  118. Cantekin EI, Bluestone CD, Fria TJ, Stool SA, Berry QC, Sabo DL. Identification of otitis media with effusion in children.  Ann Otol Rhinol Laryngol  1980;89:s190-s195

  119. Szucs E, Diependaele R, Clement PAR. The accuracy of tympanometry assessed by its sensitivity and specificity.  Acta oto-rhino-laryngologica belg  1995;49:287-92.

  120. Watters GWR, Jones JE, Freeland AP. The predictive value of tympanometry in the diagnosis of middle ear effusion.  Clin Otolaryngol  1997;22:343-5.

  121. Gates GA. Differential otomanometry.  Am J Otol  1986;7:147-50.

  122. Sassen ML, van Aarem A, Grote JJ. Validity of tympanometry in the diagnosis of middle ear effusion.  Clin Otolaryngol  1994;19:185-9.

  123. Nozza RJ, Bluestone CD, Kardatzke D, Bachman R. Identification of middle ear effusion by aural acoustic admittance and otoscopy.  Ear and Hearing  1994;15:310-23.

  124. Ovesen T, Paaske PB, Elbrond O. Accuracy of an automatic impedance apparatus in a population with secretary otitis media: principles in the evaluation of tympanometrical findings.  Am J Otol  1993;14:100-4.

  125. Palmu A, Puhakka H, Rahko T, Takala AF. Diagnostic value of tympanometry in infants in clinical practice.  Int J Pediatr Otorhinol  1999;49:207-13.

  126. Fletcher RH; Fletcher SW; Wagner EH. Clinical epidemiology:  The essentials.  3 ed. Baltimore, MD: Williams and Wilkins; 1996.

  127. McCandless GA, Thomas GK. Impedance audiometry as a screening procedure for middle ear disease.  Tr Am Opth Otol  1974;78:98-102.

  128. Labrecque M, Dostaler LP, Dumont H, Huard G, Laflamme L. Reproductibilite interobservateur d'un tympanometre portatif, le Micro Tymp.  CMAJ  1993;148:559-64.

  129. van Balen FAM, Aarts AM, De Melker RA. Tympanometry by general practitioners: reliable?  In J of Ped Otorhinolaryngol  1999;48:117-23.

  130. Pignataro O, Pignataro LD, Gallus G, Calori G, Cordaro CI. Otitis media with effusion and S-carboxymethylcysteine and/or its lysine salt: a critical overview.  In J of Ped Otorhinolaryngol  1996;35:231-41.

  131. Williams RL, Chalmers TC, Stange KC, Chalmers FT, Bowlin SJ. Use of antibiotics in preventing recurrent acute otitis media and in treating otitis media with effusion.  JAMA  1993;270:1344-51.

  132. Rosenfeld RM, Post JC. Meta-analysis of antibiotics for the treatment of otitis media with effusion.  Otolaryngology- Head and neck surgery  1992;106:378-86.

  133. Mandel EM, Casselbrant ML, Rockette HE, Bluestone CD, Kurs-Lasky M. Efficacy of antimicrobial prophylaxis for recurrent middle ear effusion.  Pediatr Infect Dis  1996;15:1074-82.

  134. van Balen FAM, De Melker RA, Touw-Otten FWMM. Double-blind randomised trial of co-amoxicalv versus placebo for persistent otitis media with effusion in general practice.  Lancet  1996;348:713-6.

  135. Marchisio P, Principi N, Passali D, Salpietro DC, Boschi G, Chetri G, Caramia G, Longhi R, Reali E, Meloni E, et al.  Epidemiology and treatment of otitis media with effusion in children in their first year of primary school.  Acta Otolaryngol (Stockh)  1998;118:557-62.

  136. Rosenfeld RM, Mandel EM, and Bluestone CD. Systemic steroids for otitis media with effusion in children. Arch Otolaryngol Head Neck Surg  1991;117984-9.

  137. Hemlin C, Carenfelt C, Papatziamos G. Single dose of betamethasone in combined medical treatment of secretory otitis media.  Ann Otol Rhinol Laryngol  1997;106:359-63.

  138. Shapiro GG, Warren Bierman C, Furukuwa CT, Pierson WE, Berman R, Donaldson J, and Rees T. Treatment of persistent Eustachian tube dysfunction with aerosolised nasal dexamethasone phosphate versus placebo. Ann Allergy  1982;4981-5.

  139. Lildholdt T and Kortholm B. Beclomethasone nasal spray in the treatment of middle- ear effusion - a double blind study. Int J Pediatr Otorhinol  1982;4133-7.

  140. Tracy JM, Demain JG, Hoffman KM, Goetz DW. Intranasal beclomethasone as an adjunct to treatment of chronic middle ear effusion.  Ann Allergy Asthma Immunol  1998;80:198-206.

  141. Maw R, Bawden R. Spontaneous resolution of severe chronic glue ear in children and the effect of adenoidectomy, tonsillectomy, and insertion of ventilation tubes (grommets).  BMJ  1993;306:756-60.

  142. Maw AR, Bawden R. The long term outcome of secretary otitis media in children and the effects of surgical treatment: a ten year study.  Acta oto-rhino-laryngologica belg  1994;48:317-24.

  143. Paradise JL, Bluestone CD, Colborn DK, Bernard BS, Smith CG, Rockette HE, Kurs-Lasky M. Adenoidenctomey and adenotonsilectomy for recurrent acute otitis media.  JAMA  1999;282:945-53.

  144. Reidpath DD, Glasziou PP, Del Mar CB. Systematic review of autoinflation for treatment of glue ear in children.  BMJ  1999;318:1177-8.

  145. Varsano IB, Volovitz BM, Grossman JE. Effect of naproxen, a prostaglandin inhibitor, on acute otitis media and persistence of middle ear effusion in children.  Ann Otol Rhinol Laryngol  1989;98:389-92.

  146. Abramovich S, O'Grady J, Fuller A. Naproxen in otitis media with effusion.  J Laryngol Otol  1986;100:263-6.

  147. Harrison H, Fixsen A, Vickers A. A randomized comparison of homeopathic and standard care for the treatment of glue ear in children.  Complementary Ther Med  1999;7(3):132-5.

  148. Maw R, Wilks J, Harvey I, Peters TJ, Golding J. Early surgery compared with watchful waiting for glue ear and effect on language development in preschool children: a randomised trial.  Lancet  1999;353:360-3.

  149. Watanabe H, Shin T, Fukaura J, Nakaaki K, Tsuda K. Total actual speaking time in infants and children with otitis media with effusion.  In J of Ped Otorhinolaryngol  1985;10:171-80.

  150. Paden EP, Novak MA, Beiter AL. Predictors of phonologic inadequacy in young children prone to otitis media.  J Speech Hearing Dis  1987;52:232-42.

  151. Manders E, Tyberghein J. The effects of ventilation tube placement on hearing, speech, language, cognition and behaviour.  Acta oto-rhino-laryngologica belg  1993;47:27-32.

  152. Orlin MN, Effgen SK, Handler SD. Effects of otitis media with effusion on gross motor ability in preschool-aged children: preliminary findings.  Pediatrics  1997;99:334-7.

  153. Lous J, Fiellau-Nikolajsen M. A 5-year prospective case-control study of the influence of early otitis media with effusion on reading achievement.  In J of Ped Otorhinolaryngol  1984;8:19-30.

  154. Lous J, Fiellau-Nikolajsen M, Jeppesen AL. Secretary otitis media and language development: a six-year follow-up study with case control.  In J of Ped Otorhinolaryngol  1988;15:185-203.

  155. Vernon-Feagans L, Manlove EE, Volling BL. Otitis media and the social behaviour of day-care-attending children.  Child Development  1996;67:1528-39.

  156. Paradise JL, Dollaghan CA, Campbell TF, Feldman HA, Bernard BS, Colborn DK, Rockette HE, Janosky JE, Pitcairn DL, Sabo DL, et al.  Language, speech sound production, and cognition in three-year-old children in relation to otitis media with effusion in their first three years of life.  Pediatrics  2000;105(5):1119-30.

  157. Friel-Patti S, Finitzo T. Language learning in a prospective study of otitis media with effusion in the first two years of life.  J Speech Hearing Res  1990;33:188-94.

  158. Shriberg LD, Friel-Patti S, Flipsen P, Brown RL. Otitis media, fluctuant hearing loss, and speech-language outcomes: a preliminary structural equation model.  J Speech Lang Hear Res  2000;43:100-20.

  159. Teele DW, Klein JO, Rosner BA, Greater Boston Otitis Media Study Group. Otitis media with effusion during the first three years of life and development of speech and language.  Pediatrics  1984;74:282-7.

  160. Teele DW, Klein JO, Chase C, Menyuk P, Rosner BA. Otitis media in infancy and intellectual ability, school achievement, speech, and language at age 7 years.  J Infect Dis  1990;162:685-594.

  161. Knishkowy B, Palti H, Adler B, Tepper D. Effect of otitis media on development: a community-based study.  Early Human Development  1991;26:101-11.

  162. Wright PF, Sell SH, McConnell KB, Sitton AB, Thompson J, Vaughn WK, Bess FH. Impact of recurrent otitis media on middle ear function, hearing and language.  J Pediatr  1988;113:581-7.

  163. Haggard M; Hughes E. Screening children's hearing: a review of the literature and the implications for otitis media. London: HMSO; 1991.

  164. Paradise, JL, Feldman HM, Campbell TF, Dollaghan CA, Colborn DK, Bernard BS, et al. Effect of early or delayed insertion of tympanostomy tubes for persistent otitis media on developmental outcomes at the age of three years. N Engl J Med 2001;344(16):1179-87.

  165. Rovers MM, Straatman H, Ingels K, van der Wilt GJ, van den Broek P, Zielhuis GA. The effect of ventilation tubes on language development in infants with otitis media with effusion: a randomized trial. Pediatrics 2000;106(3):E42.

  166. Rovers MM, Krabbe PF, Straatman H, Ingels K, van der Wilt GJ, Zielhuis GA. Randomised controlled trial of the effect of ventilation tubes (grommets) on quality of life at age 1–2 years. Arch Dis Child 2001;84(1):45-9.

Link to Recommendation Statement of this review

Link to Full Technical Report (in pdf)

Link to Structured Abstract of this review

Link to Summary Table of Recommendations of this review

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